Treatment resistant depression and the prevalence of the metabolic syndrome

This is French study by members of FondaMental from 2019. [1]

The authors investigated the prevalence of the metabolic syndrome (MetS) and its components in a cohort of French patients with treatment-resistant depression (TRD) and looked at correlations with sociodemographic, clinical, and treatment-related factors.

205 patients were enrolled in the FondaMental Advanced Centers of Expertise in Resistant Depression (FACE-DR) cohort. Data on sociodemographic and clinical characteristics, lifestyle information, and treatment and comorbidities were collected, and a blood sample was drawn. 38% of individuals with TRD met criteria for MetS. The frequency of MetS was higher than in any other psychiatric disorders and characterized by a considerable undertreatment of some components of MetS in this population.

1          Godin O, Bennabi D, Yrondi A, et al. Prevalence of Metabolic Syndrome and Associated Factors in a Cohort of Individuals With Treatment-Resistant Depression. J Clin Psychiatry 2019;80:0–0. doi:10.4088/JCP.19m12755