This is a pivotal study which was published in 2011. The authors evaluated trends in health outcomes of people with seriousmental disorders. They examined nationwide 5-year consecutive cohorts ofpeople admitted to hospital for mental disorders in Denmark,Finland and Sweden in 1987–2006. People with severe mental illness who were admitted to hospital had a two –…
This is a mediation analysis, i.e. it looks at the mechanisms that underly the known interdependence of physical and mental health. The authors investigate how social interaction and lifestyle choices mediate the effect of physical health on mental health and vice versa.
This is a systemic review and consensus statement from the American Heart Association (AHA) that was published in 2014. [1] A total of 53 studies and 4 meta-analyses were included in the review. Approximately 20% of patients admitted with an acute coronary syndrome fulfil diagnostic criteria of major depression, even more will have depressive symptoms.…
A study from the Royal Brompton in 2002. [1] The authors retrospectively examined a cohort of 396 consecutive adult patients with a dilated cardiomyopathy. In all, 83 patients (21%) were clinically depressed, the majority of which (60%) were taking antidepressant therapy. After a follow-up period of 48 months, 83 (21%) patients died, 15 (4%) underwent…
This is a meta-analysis that was published in 2001. [1] A total of 42 eligible studies were identified; 20 (48%) included a nondiabetic comparison group. In the controlled studies, the odds of depression in the diabetic group were twice that of the nondiabetic comparison group (OR 5 2.0, 95% CI 1.8 –2.2) and did not…
