HCV-infected individuals have higher prevalence of physical and psychiatric comorbidity

This is a retrospective study from Ottawa, Canada. [1] Adults aged ≥18 years with HCV (n=1209) were compared with age- and sex-matched Ottawa-area residents (n=6045).

All mental health conditions, including nonpsychotic mood and anxiety disorders (PR 2.22; 95% CI, 1.86-2.64), other mental health illnesses (PR 2.71; 95% CI, 2.06-3.55), and substance use (PR 26.50; 95% CI, 18.35-38.27) were significantly more prevalent in patients with HCV. The prevalence was significantly higher for asthma (prevalence ratio [PR] 1.32; 95% CI, 1.06-1.64), any cancer (PR 1.76; 95% CI, 1.22-2.55), COPD (PR 2.42; 95% CI, 1.73-3.39), diabetes (PR 1.32; 95% CI, 1.06-1.64), and renal failure (PR 2.92; 95% CI, 1.90-4.48). There was no difference in cardiac outcomes (arrhythmias, CHF, chronic coronary syndrome) between the two groups.

1          Cooper CL, Galanakis C, Donelle J, et al. HCV-infected individuals have higher prevalence of comorbidity and multimorbidity: a retrospective cohort study. BMC Infect Dis 2019;19:1–15. doi:10.1186/s12879-019-4315-6