659 individuals with ASD that were identified in the UK Biobank were found to have a 90% higher all case mortality when compared with 6590 matched individuals without ASD. They had a significantly higher risk of 45 medical conditions. A trajectory to death analysis showed three different clusters of conditions that were responsible for the…
This is a population based study from the US of Medicare patients. A total of 13 712 propensity score–matched pairs (adjusted to 162 covariates) were included, for an overall sample of 27 424 adults. During the median follow-up of 180 days, discontinuation vs continuation of antipsychotic medications (APM) was associated with significantly lower risks of rehospitalization, inpatient…
Among 8134 European elderly (58 % women, mean age 73 years old), median follow-up was 7.83 years. Kaplan-Meier curves showed decreasing all-cause survival with increasing numbers of comorbid physical diseases in both two groups, with higher mortality in the depression group than the non-depression group. Cox models revealed that individuals with depression and 0, 1,…
This study, which was published in the BMJ in 2012, set out to quantify the link between lower, subclinically symptomatic, levels of psychological distress and cause-mortality in a large scale, population based study. The study comprised 68,222 people from general population samples of adults aged 35 years and over, free of cardiovascular disease and cancer,…
This is a pivotal study which was published in 2011. The authors evaluated trends in health outcomes of people with seriousmental disorders. They examined nationwide 5-year consecutive cohorts ofpeople admitted to hospital for mental disorders in Denmark,Finland and Sweden in 1987–2006. People with severe mental illness who were admitted to hospital had a two –…
